citation_inspection: 43

Proposals to conduct an activity on animals. 1. Review of Protocol # 100598-0116: There was a discrepancy noted between the monitoring procedures outlined in the IACUC approved protocol and the situation observed by the APHIS inspector at the time of the inspection. The protocol states that "Rabbits are monitored following anesthesia until alert....." but during the inspection the APHIS inspector observed a Rabbit in its primary enclosure that was unconscious and in lateral recumbency. No one was in the room with the Rabbit and its medical record indicated that the animal had received an injection of an anesthetic a little over 2 hours ago and an injection of an analgesic less than ½ hour ago; both of the medications had been administered by research personnel. Per this Section of the Regulations, a proposal for animal use must contain a description of the procedures designed to assure that any discomfort and pain to animals will be limited to that which is unavoidable for the conduct of scientifically valuable research, including provisions for the use of analgesic, anesthetic, and tranquilizing drugs where indicated and appropriate. Research personnel are expected to follow animal use procedures as they are described in the IACUC approved protocol. The IACUC needs to address the discrepancy identified for this ongoing IACUC approved research proposal. Correct by 8/21/14.